A Real-World Study on Ultrasound-Based Screening and Integrated Therapeutic Strategies for Patients With Concomitant Coronary and Cervicocephalic Artery Stenosis
Trial Snapshot
- Phase
- Not Applicable
- Status
- Recruiting
- Sponsor
- Enrollment
- 1,000
- Locations
- 1
- Primary Endpoint
- Prevalence of Head and Neck Artery Stenosis in Patients with Coronary Artery Disease
Study Overview
Brief Summary
This prospective observational cohort study aims to investigate the prevalence and clinical significance of head and neck arterial stenosis in patients with coronary artery disease (CAD) undergoing or scheduled for percutaneous coronary intervention (PCI). Using Doppler ultrasound as the primary screening tool, the study will assess the degree of stenosis and evaluate the impact of different combined treatment strategies on patient outcomes. The research will provide real-world evidence to optimize integrated care approaches for patients with comorbid cardiovascular and cerebrovascular diseases.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Age ≥18 years;
- •Patients with coronary artery disease scheduled to undergo elective percutaneous coronary intervention (PCI) on the following day.
Exclusion Criteria
- •The expected survival is less than 1 years;
- •Simultaneously merge other serious diseases;
Outcomes
Primary Outcomes
Prevalence of Head and Neck Artery Stenosis in Patients with Coronary Artery Disease
Time Frame: At baseline (prior to or during initial hospitalization)
The proportion of patients with coronary artery disease who are found to have head and neck artery (e.g., carotid or vertebral artery) stenosis, as determined by duplex ultrasound or other imaging modalities.
Secondary Outcomes
- mRS Score(365±30 days)
- mRS score(7±1 days or the day discharged)
- Rate of cardiovascular and cerebrovascular events(365±30 days)
- Short-term complications(90±7 days)
- Long-term complications(365±30 days)
Investigators
Xiaochuan Huo
Prof
Beijing Anzhen Hospital