Efficacy of pulsed radiofrequency ablation for the treatment of oarl cancer pain involving glossopharyngeal nerve.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Efficacy of PRF ablation of glossopharyngeal nerve for the treatment of cancer pain by pain score by numerical rating scale
研究概览
简要总结
The Pulsed Radiofrequency (PRF) treatment has been used previously for the treatment of various pain conditions and found to be safe & effective.In this trial we will study whether PRF treatment of glossopharyngeal nerve is effective & safe in the pain management of oropharyngeal cancer patient suffering from intractable pain which can not be controlled by traditional analgesic therapy at base of tongue, tonsillar fossa, oropharynx( area supplied by glossopharyngeal nerve). PRF of glossopharyngeal nerve will be done at Operation theatre under full aseptic precaution with standard monitoring for vital signs & as day care basis. Post procedure patient will be monitored at PACU for 2 hrs and subsequently patient will be assessed at 1 week, 2week. 1 month, 2 month, 3 month post PRF at pain clinic. During their visit pain score will be noted according to numerical rating scale ( NRS). Treatment will be considered effective if there is 50% reduction in NRS at 2 week post PRF from the base line.
研究设计
- 研究类型
- Interventional
- 分配方式
- Not Applicable
- 盲法
- Open Label
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •Adult population (18-65 years)suffering from oropharyngeal carcinoma with no curative intervention planned( not fit for surgery) undergoing treatment by WHO step ladder II method still complaining of severe pain ( NRS>5) in the base of tongue, tonsillar fossa, pharynx- area mainly supplied by glossopharyngeal nerve.
排除标准
- •unstable cardio-respiratory disorder coagulation & hematological disorder psychological disorder & history drug abuse non compliant for 3 months follow up injection site not suitable due to presence of infection , lymph node enlaegement bilateral involvement of glossopharyngeal nerve.
结局指标
主要结局
Efficacy of PRF ablation of glossopharyngeal nerve for the treatment of cancer pain by pain score by numerical rating scale
时间窗: Post intervention - 1week, 2 week, 1 month, 2 month, 3 month
次要结局
- Safety profile of PRF of glossopharyngeal nerve in cancer pain(during & post intervention (120 mins ) & post intervention 1 week, 2 week, 1 month, 2 month,3 month)