Somatic Symptoms in Autism Spectrum Disorder: Data Integration
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Autism Spectrum Disorder
- Sponsor
- National Taiwan University Hospital
- Enrollment
- 1423
- Primary Endpoint
- Patient health questionnaire-15, PHQ-15
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
Autistic patients have higher chances commorbid somatic symptoms. Therefore, it leads to more health-related concerns, such as autoimmune disease, gastrointestinal disease, cardiovascular disease, autonomic disorders. On average, autistic patient's life span is 16 years shorter than non-autistic patients. Furthermore, autistic patients are not able to convey or communicate their somatic symptoms in a clear and comprehensive manner. This leads to unable to receive proper health care in a timely manner.
Investigators
Eligibility Criteria
Inclusion Criteria
- •ASD group: diagnosed with DSM-5 autism spectrum disorder
- •clinical group: anxiety, depression, somatic disorder who are non-psychotic and non-organic
- •control group: healthy control without psychiatric disorder or chronic somatic symptoms
- •age between 15 and 70
Exclusion Criteria
- •psychiatric disorders such as schezophrenia, mood disorder.
- •major physical disorder which can be potentially lethal
- •who cannot read or comprehend the survey and questionnaire
Outcomes
Primary Outcomes
Patient health questionnaire-15, PHQ-15
Time Frame: 8 years
range from 0 to 2 for each item, total score range from 0 to 30. Higher the score, worse the level of somatization
Health assessment questionnairse, HAQ
Time Frame: 8 years
range from 0 to 3 for each item. Higher the score, worse the disability
Beck depression inventory, BDI
Time Frame: 8 years
range from 0 to 3 for each item. Higher the score, worse the depression
Beck anxiety inventory
Time Frame: 8 years
range from 0 to 3 for each item. Total score 0 to 63. Higher the score, worse the anxiety