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Clinical Trials/NCT05564013
NCT05564013
Not yet recruiting
Not Applicable

Developing a Virtual Reality (VR)-Based Prototype for Perioperative Care - a Proof of Concept Study

Changi General Hospital1 site in 1 country160 target enrollmentOctober 2022

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Anxiety
Sponsor
Changi General Hospital
Enrollment
160
Locations
1
Primary Endpoint
Pre-operative anxiety
Status
Not yet recruiting
Last Updated
3 years ago

Overview

Brief Summary

Preoperative anxiety and acute post-operative pain are common and have been associated with the development of chronic post-surgical pain and longer hospitalisation. Pharmacological interventions to combat anxiety and pain come with their attendant adverse effects. Therefore, non-pharmacological strategies- Virtual Reality (VR) has gained popularity to improve overall the perioperative experience for patients.

Our overall aim is to develop and evaluate the use of a VR-based prototype to reduce pre-operative anxiety and post-operative acute pain intensity in our local patient population. Our primary aim is to reduce preoperative anxiety as measured by a reduction in Visual Analogue Score-Anxiety (VAS-A) by a mean of 2.5 points pre-post VR intervention. Our secondary aims are to reduce post-operative acute pain and to achieve more than 50% good to excellent self-reported satisfaction on our VR prototype.

Detailed Description

This will be a multi-center, prospective cohort study to be conducted in Changi General Hospital (CGH) and KKH, in collaboration with industry partner, Vue Networks. The patients will provide written informed consent for the study. Phase 1: To facilitate the development of VR application that is suitable for perioperative care management, a survey will be conducted in 100 subjects (CGH: n=50; KKH: n=50) to gather patient preference and feedback with needs analysis. The VR application development needs analysis would focus on: i) instructional module on surgical journey; and ii) mindfulness module with inputs from perspectives of clinical health psychology iii) local relaxation scenarios (e.g. village, botanic gardens, Changi beach, Gardens by the bay); iv) feedback on hardware, i.e., VR headset usability. Phase 2: The testing of the developed VR application will be performed in 60 subjects (CGH: n=30; KKH: n=30). The study will utilize Head-Mounted Displays (HMD) such as the PicoG2 4K, the Oculus Go and/or Quest headsets. In immersive VR, high resolution 360-degree video and/or 3D computer graphics are paired with suitable ambience sounds and audio cues to fully immerse the user in the selected environment. The contents comprise a mixture of live-action and/or animation, as well as local settings. The domain components of the VR intervention include: * VR application for pre-operative anxiety and post-operative acute pain treatment with local context; * Patient feedback on local scenarios and content of VR and mindfulness; * Development of VR application: Vue Networks' platform with local and foreign context scenarios, passive and active scenario features, development of mindfulness application, language use for mindfulness application.

Registry
clinicaltrials.gov
Start Date
October 2022
End Date
September 2023
Last Updated
3 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Lydia Li Weiling

Consultant, Department of Anaesthesia and Surgical Intensive Care

Changi General Hospital

Eligibility Criteria

Inclusion Criteria

  • Adult patients aged 21 years old and above and undergoing scheduled surgery;
  • American Society of Anesthesiologist physical status I to III, with no visual or hearing impairment; and
  • Understands English or Chinese.

Exclusion Criteria

  • Comorbidities affecting usage of virtual reality e.g., giddiness, motion sickness, claustrophobia, stroke, seizure, dementia, transmissible diseases, severe facial eczema; and
  • Unable to understand the administered questionnaires.

Outcomes

Primary Outcomes

Pre-operative anxiety

Time Frame: up to 1hour

Anxiety score - VAS-A (0 to 10; 0-best outcome, 10-worst outcome)

Secondary Outcomes

  • Post-operative pain(up to 1hour)
  • User satisfaction(up to 1hour)

Study Sites (1)

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