Comparison of Morphine and Methadone on Postoperative Pain of Opioid Addicted Patients in Major Orthopedic Surgery
Phase 2
- Conditions
- Condition 1: Opium Addiction. Condition 2: Orthopaedic Surgery.Mental and behavioural disorders due to use of opioidsFracture of Bone following Insertion of Orthopaedic Implant, Joint Prosthesis, or Bone Plate
- Registration Number
- IRCT2014100919470N1
- Lead Sponsor
- Vice Chancellor for Research, Shiraz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 68
Inclusion Criteria
opium -addicted patients, aged of 18-70 years undergoing major orthopedic surgeries.
Exclusion criteria: patients with a history of myocardial infarction, heart failure, patients with ASA class above III, patients using anti-depressant drugs, a history of allergy to the drugs and patients who need ICU after surgery.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Evaluation of the postoperative pain in major orthopedic surgery in patients addicted to opium. Timepoint: Immediately after surgery and one hour, three hours, six hours and 24 hours after surgery. Method of measurement: NRS.
- Secondary Outcome Measures
Name Time Method Patient's satisfaction. Timepoint: Immediately after surgery and one hour, three hours, six hours and 24 hours after surgery. Method of measurement: Four Point Categorical Scale.