Haemolysis during extracorporeal CO2 removal; a laboratory study using donated human blood.
Completed
- Conditions
- Haemolysis, extracorporeal CO2 removal, low flow CO2 removal, extracorporeal life support, ELS, COPD, exacerbation, chronic obstructive pulmonary disease, acute lung failure.Hemolyse, extracorporale CO2 verwijdering, extracorporale ondersteuning, exacerbatie, acuut longfalen.
- Registration Number
- NL-OMON25081
- Lead Sponsor
- niversity Medical Centre
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 30
Inclusion Criteria
Healthy volunteer.
Age and gender not relevant.
Exclusion Criteria
Volunteers known with anaemia or those not feeling well.
Volunteer that has taken part in this study and has donated blood during the past 7 days.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ormalised index of haemolysis (NIH).*<br><br /><br /><br>*Plasma free haemoglobin is measured in duplo at the beginning and end of an in vitro run in order to calculate the NIH.
- Secondary Outcome Measures
Name Time Method Pump speed (in rpm).<br /><br>In vitro circuit pressures (in mmHg). <br /><br>In vitro circuit temperature (in oC).<br>