Tramadol hydrochloride vs lignocaine hydrochloride in the extraction of anterior teeth - comparative study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Pain with VAS score
研究概览
简要总结
Background
The aim of this study was to compare the local anesthetic effect of tramadol with that of lignocaine in the extraction of maxillary anterior teeth.
CLINICAL RELEVANCE
Scientific rationale for the study: The study emphasizes the necessity of choosing the right local anesthetic to ensure adequate pain relief during dental treatments.
Principal findings: We found that tramadol can also be used as an anesthetic agent. Although it is not as potent as lignocaine, a higher quantity of tramadol is required to obtain the desired amount of anesthesia, and has a faster onset of action.
Practical implications: Lignocaine is still the gold standard because of its superior efficacy and safety profile. Tramadol, on the other hand, may have importance in some situations , such as in patients who are allergic to lignocaine or other conventional local anesthetics. In such circumstances, tramadol could be administered as an adjuvant to improve the overall anesthetic effect, although greater dosages may be required to achieve effective pain management.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients requiring extraction of one or more maxillary anterior teeth and providing informed consent.
排除标准
- •Patients with known allergies to lignocaine or tramadol, those with significant medical conditions contraindicating dental extractions, pregnant or lactating women, and patients on medications that could interfere with pain perception or local anesthesia.
结局指标
主要结局
Pain with VAS score
时间窗: At baseline
次要结局
- Onset of anesthesia in minutes(At baseline)
- Amount of anesthesia administered in number of vials(At baseline)
研究者
Srishti Agarwal
Saveetha dental college and hospital