Diagnostic Prediction of Pancreatic Masses

Completed

• Conditions: Pancreatic Masses

• Registration Number: NCT06724055
• Lead Sponsor: Peking Union Medical College Hospital

Brief Summary

The goal of this observational study is to learn if a strategy can be developed for differentiating autoimmune pancreatitis (AIP) and primary pancreatic lymphoma (PPL) from pancreatic ductal adenocarcinoma (PDAC) in patients presenting with pancreatic masses. The main question it aims to answer is:

What features, in the perspectives of clinical manifestation, laboratory tests, and imaging, can differentiate different kinds of pancreatic masses (AIP, PPL and PDAC)?

Participants will not be given any interventions since this is a retrospective observational study.

Detailed Description

Not available

Study Timeline

• Study Start: 2002-01-01
• Primary Completion: 2023-05-31
• Study Completion: 2023-05-31
• Status Verified: 2024-11
• Study First Submitted: 2024-11-18
• Study First Submitted QC: 2024-12-06
• Last Update Submitted: 2024-12-06
• Study First Posted: 2024-12-09
• Last Update Posted: 2024-12-09

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 110

Inclusion Criteria

• Inpatients presenting with pancreatic masses and eventually diagnosed with PPL, AIP, or PDAC (confirmed by pathologic results).

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Diagnostic nomogram	From date of admission into the hospital to the establishment of diagnosis, assessed up to 100 months

Secondary Outcome Measures

Name	Time	Method
serum level of LDH	From date of admission into the hospital to the establishment of diagnosis, assessed up to 100 months
serum level of IgG4	From date of admission into the hospital to the establishment of diagnosis, assessed up to 100 months
largest diameter of pancreatic masses	From date of admission into the hospital to the establishment of diagnosis, assessed up to 100 months
dilation of pancreatic duct	From date of admission into the hospital to the establishment of diagnosis, assessed up to 100 months