NCT01550861终止不适用
In Vitro Maturation (IVM) of Human Oocytes
适应症
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 2
- 试验地点
- 1
- 主要终点
- number of oocytes retrieved and embryos generated
研究概览
简要总结
The objectives of this study are to evaluate the clinical efficacy of Natural in vitro Fertilization and in vitro maturation.
详细描述
Collection of one mature egg from a follicle in the ovary without gonadotropin medications (natural cycle IVF) results in low pregnancy rates. One way to improve natural cycle IVF is to combine this procedure with the removal of immature eggs from the ovary and mature these eggs in the laboratory ( in vitro maturation-IVM). The in vitro mature eggs are fertilized and the resultant embryos are cultured using conventional IVF techniques.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 25 Years 至 42 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Each subject must be female.
- •Each subject must have an indication for COH and IVF with or without ICSI.
- •Each subject must be willing and able to provide written informed consent for the trial
- •Each subject must be 25 to ≤42 years of age at the time of signing informed consent.
- •Each subject must have a normal cervical smear result (no atypical or abnormal cells, or in case of atypical squamous or glandular cells, no signs of malignancy; corresponding to Papanicolaou [PAP] I or II) obtained within 12 months prior to signing informed consent must be available
排除标准
- •Subject with premature ovarian failure
- •Subject with endocrine abnormalities such as hyperprolactinaemia or thyroid dysfunction
- •Subject with malformation or absence of uterus
- •Subject has tested positive for Human Immunodeficiency Virus (HIV) or Hepatitis B (by local laboratory; results obtained within 1 year prior to signing ICF are considered valid).
- •Subject with contraindication or allergy/hypersensitivity to hCG, estrogen and progesterone
结局指标
主要结局
number of oocytes retrieved and embryos generated
时间窗: 1 year
次要结局
- live birth rate(1 year)
研究者
研究点 (1)
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