A phase II study to evaluate the effect on the combination chemotherapy of CPT-11 and S-1 for advanced/recurrent colon cancer which combines genetic analysis on adverse events (OGSG 0405)
- Conditions
- Patients with advanced and/or recurrent colon cancer
- Registration Number
- JPRN-UMIN000000855
- Lead Sponsor
- OGSG
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 30
Not provided
1. without interstitial pneumonia or pulmonary fibrosis on X-ray examination And/or clinical signs 2. Cavity fluid which needs drainage 3. with active double cancer except ca. in situ 4. with intestinal paralysis or obstruction 5. under watery diarrhea 6. with uncontrolled DM 7. with ischemic cardiac disease 8. with mental disorder which disturbs registration to this study 9. with infectious disease which needs treatment 10. patients who receive steroids treatment 11. Cardiac failure, liver dysfunction, or renal dysfunction which disturb Registration to this study 12. with brain metastasis and the symptom due to the metastasis 13. pregnant women or women who like to be pregnant 14. history of severe allergy against drug 15. doctor's dicision not to be registered to this study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Response Rate
- Secondary Outcome Measures
Name Time Method adverse events, survival time, Relative Performance, Genomic instability