Effect of yoga on stress, immunity and sleep in menstrual cycle

Not yet recruiting

• Conditions: Healthy

• Registration Number: CTRI/2025/05/086469
• Lead Sponsor: All India Institute of Medical Sciences, New Delhi

Brief Summary

Menstrual cycle is a repetitive phenomenon occurring every 21-45 days during the reproductive life of a female that involves structural, functional & hormonal changes in the reproductive system. The follicular and luteal phases of the menstrual cycle involve significant hormonal fluctuations, which impact stress levels, sleep patterns, and immune function. Understanding how yoga-based interventions affect these changes can offer non-pharmacological solutions for better health management. Yoga is known to influence the hypothalamic-pituitary-adrenal (HPA) axis, which regulates stress and immunity. Investigating its effects in the context of the menstrual cycle helps establish a connection between lifestyle practices and hormonal health. Women often report disturbed sleep during different phases of their cycle. Yoga’s potential to enhance sleep quality could provide significant insights into managing menstrual-related sleep issues. Hormonal shifts during the menstrual cycle can impact immunity. This study may provide evidence of yoga’s role in strengthening or stabilizing immune responses during these phases. By targeting specific phases of the menstrual cycle, the research could lead to phase-specific lifestyle recommendations, contributing to the field of personalized medicine and holistic health. The study could validate yoga as an effective, low-cost, and non-invasive method to manage stress, improve sleep, and enhance immunity, benefiting a wide range of individuals. This study addresses a critical gap in understanding how lifestyle interventions can improve overall well-being in the context of menstrual cycle-related changes.

Detailed Description

Not available

Study Timeline

• Study Start: 2025-05-20
• Last Update Posted: 2025-06-05

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: Female
• Target Recruitment: 30

Inclusion Criteria

1.Regular menstrual cycle, varying from 24-32days 2.Menstrual phase lasting upto 7 days 3.Menstrual product use: Three to six pads or tampons per day 4.Flow volume should be normal 5.No intermenstrual bleeding 6.No prior yoga intervention in last 8 weeks.

Exclusion Criteria

1.History of any gynecological disorders including PCOS 2.Use of oral contraceptive pills 3.Any thyroid disorders, or immune disorders, autoimmune disorders 4.Substance abuse 5.Any diagnosed sleep disorders.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To evaluate the effects of short-term YBLI in follicular and luteal phase of regular menstrual cycle on:	There will be 4 time points: at baseline, after 2 weeks, 4 weeks and 6 weeks .
1.Immunity : T cell,B cell,NK cell	There will be 4 time points: at baseline, after 2 weeks, 4 weeks and 6 weeks .
2.Stress : Cortisol	There will be 4 time points: at baseline, after 2 weeks, 4 weeks and 6 weeks .
3.Sleep : Melatonin	There will be 4 time points: at baseline, after 2 weeks, 4 weeks and 6 weeks .

Secondary Outcome Measures

Name	Time	Method
To correlate the stress, sleep and immunity parameters with phases of menstrual cycle and premenstrual symptoms of the participants.	There will be 4 time points: at baseline, after 2 weeks, 4 weeks and 6 weeks .

Trial Locations

Locations (1)

AIIMS, New Delhi; 🇮🇳 South, DELHI, India

AIIMS, New Delhi

🇮🇳South, DELHI, India

Dr Raj Kumar Yadav

Principal investigator

raj3kr@gmail.com