Establishing how many patients with HIV are infected with Kala Azar but show no symptoms, bit then go on to develop symptoms over 18 months.
Not Applicable
- Conditions
- Health Condition 1: null- HIV positive patients under routine monitoring care at ART centres
- Registration Number
- CTRI/2017/03/008120
- Lead Sponsor
- Medecins Sans Frontires India
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 1000
Inclusion Criteria
1 Registered ART/pre-ART patients with either a new or established diagnosis of HIV
2 Written consent
Exclusion Criteria
1 Previous treatment for, or current diagnosis of symptomatic visceral leishmaniasis or PKD
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method - Determine prevalence of asymptomatic VL cases in HIV cases registered at ART centres from highly VL endemic areas <br/ ><br> <br/ ><br>- Determine the rate of conversion of asymptomatic VL cases into symptomatic VL over a period of 18 months. <br/ ><br>Timepoint: - Determine prevalence of asymptomatic VL cases in HIV cases registered at ART centres from highly VL endemic areas <br/ ><br> <br/ ><br>- Determine the rate of conversion of asymptomatic VL cases into symptomatic VL over a period of 18 months. <br/ ><br>
- Secondary Outcome Measures
Name Time Method - To correlate results of rk39 ICT with qPCR in PLHIV. <br/ ><br>- To determine risk factors for progression of asymptomatic cases to symptomatic VL over a follow up period of 18 months in PLHIV. <br/ ><br>Timepoint: 18 months