Effectiveness of cognitive retraining on neuropsychological, neuroimaging correlates and quality of life following epilepsy surgery: a randomized control study

ational Institute of Mental Health and Neurosciences0 个研究点目标入组 43 人开始时间: 2021年12月14日最近更新: 2021年12月27日

适应症

试验速览

暂无简介。

•1. Patients diagnosed with DRE with HS or dual pathology (FCD) within the resected area as determined by pre-surgical imaging and other neurological examinations from the neurosurgery inpatient and outpatient services of NIMHANS
•2. Patients who have subsequently undergone ATL-AH and are stabilized on anti-epileptic drugs (AEDs) over a period of 6 months to 7 years post-surgery
•3. Patients with 1A outcome of surgery on Engel’s classification system
•4. Patients within 18 to 50 years of age
•5. Patients who are right-handed
•6. Patients with at least the ability to read and write in one language
•7. Patient with language fluency in Hindi, English or Kannada
•8. Patients with adequate/corrected auditory, visual and/or motor function
•Healthy controls:
•1. Individuals matching with the Intervention group participants on gender, age and education within ±2 SD range
•2. Individuals within 18 to 50 years of age
•3. Individuals who are right handed
•4. Individuals with and ability to read and write in one language
•5. Individuals with language fluency in Hindi, English or Kannada
•6. Individuals with adequate/corrected auditory, vision and sensory-motor functions

•1. Patients diagnosed as having double pathology or extra-temporal pathology
•2. Patients who have undergone surgery before the age of 12 years
•3. Patients who have undergone multiple surgeries for epileptic seizures or any other neurological condition
•4. Patients with any outcome of seizure other than 1A on Engel’s classification system
•5. Patients with a history of intellectual disability
•6. Patients who have undergone any form of psychological intervention
•7. Patients with any other neurological, medical and psychiatric conditions including substance abuse
•Healthy controls:
•1. Individuals with a history of intellectual disability
•2. Individuals who have undergone any form of psychological intervention.
•3. Individuals with any other psychiatric (including substance abuse) and neurological conditions
•4. Individuals with a history of medical conditions

发起方

ational Institute of Mental Health and Neurosciences