ProActive Athlete Heart Program: Proposal for Cardiac Risk Screening in Former High-Intensity Athletes
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Prevalence of Coronary Atherosclerosis
研究概览
简要总结
AI-Guided Coronary CT Angiography Screening in Former High-Intensity Athletes
详细描述
A prospective, interventional, single-center study to determine the prevalence and characteristics (burden, composition, risk features) of coronary atherosclerosis in former high-intensity athletes using AI-guided software to analyze a CCTA.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Screening
- 盲法
- None
入排标准
- 年龄范围
- 30 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Former professional or collegiate high-intensity athletes (e.g., NFL alumni, Division I athletes, or equivalent competitive-level participants).
- •Age ≥30 years
排除标准
- •eGFR <40 mL/min/1.73 m²
- •Known iodinated contrast allergy
- •Weight >450 lbs. (scanner table limit)
- •Inability to hold breath >10 seconds
- •Uncontrolled arrhythmia
- •Contraindication to beta-blocker, Calcium Channel Blockers and nitroglycerin
- •Taking part in another research study that has not given their permission to participate in this one
- •Pregnancy
研究组 & 干预措施
Athletes
This arm will have answer a questionnaire, have a physical exam performed as well as a Coronary CTA and labs completed. The Coronary CTA images will be analyzed using AI-software to assess plaque quantification and an ischemia analysis.
干预措施: Coronary CTA (Device)
结局指标
主要结局
Prevalence of Coronary Atherosclerosis
时间窗: At CCTA assessment
The primary outcome is to determine the prevalence of coronary atherosclerosis in former high-intensity athletes using AI-guided software to analyze a CCTA.
Coronary Atherosclerosis Characteristics
时间窗: At CCTA Assessment
Determine the characteristics (burden, composition, risk features) of coronary atherosclerosis in former high-intensity athletes using AI-guided software to analyze a CCTA.
次要结局
- Plaque Burden(Day of CCTA and biomarker collection)