NCT00434486已完成1 期
An Open-Label, Randomized, 2-Period Crossover Study to Evaluate the Potential Pharmacokinetic Interaction Between Multiple Doses of Ketoconazole and a Single Dose of SKI-606 Administered Orally to Healthy Subjects
Wyeth is now a wholly owned subsidiary of Pfizer1 个研究点 分布在 1 个国家目标入组 24 人开始时间: 2007年3月1日最近更新:
适应症
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 发起方
- 入组人数
- 24
- 试验地点
- 1
- 主要终点
- Pharmacokinetics; safety and tolerability
研究概览
简要总结
To investigate a potential pharmacokinetic interaction between SKI-606 and ketoconazole when co-administered.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy as determined by the investigator on the basis of medical history, physical examination, clinical laboratory test results, vital signs, and 12-lead ECG.
排除标准
- 未提供
结局指标
主要结局
Pharmacokinetics; safety and tolerability
次要结局
未报告次要终点
研究者
研究点 (1)
Loading locations...
相似试验
已完成
1 期
HKI-272 Ketoconazole Drug Interaction StudyHealthyNCT00380328Puma Biotechnology, Inc.24
已完成
1 期
A Study to Assess Pharmacokinetic Interaction of Multiple Dose Ketoconazole on Single Dose YM178 Oral Controlled Absorption System (OCAS) in Healthy Adult VolunteersHealthy SubjectsPharmacokinetics of YM178NCT01476800Astellas Pharma Inc24
已完成
1 期
Drug-Drug Interaction (DDI) w/Ketoconazole or FluconazoleAlzheimer DiseaseNCT00860275Bristol-Myers Squibb30
已完成
1 期
Study to Determine the Impact of Multiple Doses of Ketoconazole on Single-Dose Pharmacokinetics of HCV-796HealthyNCT00384917Wyeth is now a wholly owned subsidiary of Pfizer24
已完成
1 期
Drug-drug Interaction Study (CKD-501, Ketoconazole)Type 2 Diabetes MellitusNCT01330563Chong Kun Dang Pharmaceutical24