Study Evaluating Drug Interaction Between Multiple Doses of Ketoconazole and a Single Dose of SKI-606

Phase 1

Completed

• Conditions: Healthy

• Registration Number: NCT00434486
• Lead Sponsor: Wyeth is now a wholly owned subsidiary of Pfizer

Brief Summary

To investigate a potential pharmacokinetic interaction between SKI-606 and ketoconazole when co-administered.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2007-02-09
• Study First Submitted QC: 2007-02-12
• Study First Posted: 2007-02-13
• Study Start: 2007-03
• Study Completion: 2007-03
• Status Verified: 2007-09
• Last Update Submitted: 2007-09-10
• Last Update Posted: 2007-09-12

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

• Healthy as determined by the investigator on the basis of medical history, physical examination, clinical laboratory test results, vital signs, and 12-lead ECG.

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Primary Outcome Measures

Name	Time	Method
Pharmacokinetics; safety and tolerability