Addressing low treatment rates of chronic hepatitis C in injecting drug users

Not Applicable

Completed

• Conditions: Hepatitis C virus treatment; Infections and Infestations; Acute hepatitis C

• Registration Number: ISRCTN07774040
• Lead Sponsor: Barts and the London NHS Trust (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2014-06-19
• Last Update Posted: 3 April 2017

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 402

Inclusion Criteria

1. Hepatitis C virus (HCV) positive (as shown by a positive HCV RNA level)
2. Attending Specialist Addiction Services in the boroughs of Hackney, Newham or Tower Hamlets in London

Exclusion Criteria

1. A negative test for HCV infection
2. People who are not registered with specialist addiction services
3. Those who have evidence of any of the following:
4. Cirrhosis of the liver - blood test, imaging or liver biopsy evidence
5. Anaemia (low red cells) Haemoglobin <12
6. Thrombocytopenia (low platelet count) <150
7. Lymphopenia (low white cells) < 3
8. Active infection of any kind
9. Serious psychiatric disorders in the last two years
4. Uncontrolled asthma
5. Chronic obstructive pulmonary disease
6. Ischaemic heart disease, or severe cardiac disease including ventricular arrhythmias, angina and heart failure, renal failure, autoimmune disease

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. Number of patients who achieve a sustained viral response<br>2. Number of patients who are compliant with treatment<br>3. Number of patients who start and finish treatment

Secondary Outcome Measures

Name	Time	Method
Change in alcohol and drug use of participants