Proton beam therapy for intrahepatic cholangiocarcinoma unsuitable for surgery or chemotherapy
- Conditions
- Intrahepatic cholangiocarcinoma
- Registration Number
- JPRN-UMIN000020862
- Lead Sponsor
- Department of Radiation Oncology, University of Tsukuba Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 30
Not provided
1)Postoperative recurrence 2)Presence of lymph nodes metastases 3)Presence of distant metastases 4)Presence of active double cancers 5)Infection required systematic therapy 6)Body temperature more than 38 degree Celsius at screening 7)Pregnacy,demand of pregnant,28 days within childbirth and lactating 8)Psychosis or complicated mental symptom which causes difficult to entry 9)Steroid or other immunosuppressive drugs usage 10)Uncontrolled diabetes 11)Uncontrolled hypertension 12)Unstable angina within 3 weeks of myocardial infarction within 6 months 13)Presence of interstitial pneumonitis, pulmonary fibrosis, or severe emphysema which is diagnosed by chest CT 14)Esophageal varix (hemorrhagic,history of hemorrhage, more than F2,RC2) 15)Inappropriate decision by a principal investigator 16)Entry to other clinical research
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 2-year overall survival rate
- Secondary Outcome Measures
Name Time Method 1)2-year progression free survival rate 2)2-year local progression free survival rate 3)Adverse effect frequency 4)Radiation induced liver disease