Nasopharyngeal Airway Facilitate Transnasal Humidified Rapid Insufflation Ventilatory Exchange
试验速览
- 阶段
- 不适用
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- The partial pressure of oxygen(PO2)
研究概览
简要总结
For performing transnasal humidified rapid insufflation ventilatory exchange (THRIVE), jaw-thrust maneuver have to maintain to make sure the airway open and the CO2 clearance during apnoea. The objective of present study is to prove that nasopharyngeal airway facilitate THRIVE and no need jaw-thrust maneuver and maintain the similar PO2 and PCO2 during apnoea.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Signed informed consent.
- •Undergoing surgery with general anaesthesia.
- •Adult, >18 years old.
- •American Society of Anesthesiology classification I-II.
排除标准
- •Coagulation disorders or a tendency of nose bleeding
- •An episode/exacerbation of congestive heart failure (CHF) that requires a change in medication, diet or hospitalization from any cause in the last 6 months
- •Severe aortic stenosis or mitral stenosis;
- •Cardiac surgery involving thoracotomy (e.g., coronary artery bypass graft (CABG), valve replacement surgery) in the last 6 months;
- •Acute myocardial infarction in the last 6 months;
- •Acute arrhythmia (including both tachycardia and bradycardia) with hemodynamic instability;
- •Diagnosed COPD or current other acute or chronic lung disease requiring supplemental chronic or intermittent oxygen therapy);
- •Increased intracranial pressure;
- •ASA >II;
- •Mouth, nose, or throat infection;
- •Fever, defined as core body temperature > 37.5°C;
- •Pregnancy, breastfeeding or positive pregnancy test;
- •Emergency procedure.
- •Patient with known or suspected difficult airway
研究组 & 干预措施
THRIVE
Transnasal humidified rapid-insufflation ventilatory exchange (THRIVE) during induction using jaw-thrust maneuver.
THRIVE with nasopharyngeal airway
Transnasal humidified rapid-insufflation ventilatory exchange (THRIVE) during induction with nasopharyngeal airway.
干预措施: Nasopharyngeal airway (Device)
结局指标
主要结局
The partial pressure of oxygen(PO2)
时间窗: From start to end of THRIVE(20 minutes)
The partial pressure of carbon dioxide (pCO2)
时间窗: From start to end of THRIVE(20 minutes)
次要结局
未报告次要终点