Study of Surgical Methods for Repair of Clean Transections in Peripheral Nerve Injuries
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 46
- 试验地点
- 1
- 主要终点
- motor function
研究概览
简要总结
The purpose of this study is to determine which surgical approach is better for clean transection injury in peripheral nerves in outcomes.
详细描述
Treatment of injuries to major nerve trunks in the hand and upper extremity remains a major and challenging reconstructive problem. Our goal was to compare primary versus secondary repair of median and\or ulnar nerve by electrodiagnostic assessment and clinical examination.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •patients with confirmed clean transection injury between shoulder and wrist
排除标准
- •crush injuries
研究组 & 干预措施
secondary repair
secondary closure beyond the first week.the nerve was conducted to repair as end to end (epi-epineurium, epi-epineurium) anastomosis. This was performed following the repair of present tendons and muscle injuries.
干预措施: secondary repair (Procedure)
primary repair
during first days,the nerve was conducted to repair as end to end (epi-epineurium, epi-epineurium) anastomosis. This was performed following the repair of present tendons and muscle injuries.
干预措施: primary repair (Procedure)
结局指标
主要结局
motor function
时间窗: at 18 months post-operatively
identification of motor level were done based on British Medical Research Council guided.The abductor pollicis brevis (APB) was used for the median nerve and the abductor digiti minimi (ADM) for the ulnar nerve. as follows: 0, M0, M1 and M2; 1, M3; 2, M4.
次要结局
- sensory recovery(at 18 months post-operatively)
- nerve conduction velocity(at 18 months post-operatively)
- electromyography(at 18 months post-operatively)