The Effect of Placental Cord Drainage on the Third Stage of Labor and the Amount of Postpartum Bleeding
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 80
- 试验地点
- 2
- 主要终点
- Determining the duration of the third stage of labor
研究概览
简要总结
The aim of the study was to evaluate the effect of controlled placental cord drainage by opening the clamp at the maternal end after the umbilical cord is cut during birth on the duration of the third stage of labor (departure of the placenta), the amount of blood loss in the third stage, the amount of bleeding in the 2nd hour postpartum, and the development of postpartum complications.
详细描述
Although the third stage is the shortest stage of labor, it is also the riskiest. Prolonging this stage increases the risk of complications, particularly postpartum hemorrhage. Therefore, the duration of the third stage of labor should be as short as possible. Internationally accepted labor management guidelines, such as WHO and ACOG, recommend that active management be adopted to shorten the third stage of labor to prevent postpartum hemorrhage. Placental cord drainage is also mentioned in the literature as a method used to accelerate the delivery of the placenta by actively managing the third stage of labor. This method involves clamping and cutting the umbilical cord after the birth of the baby, then opening the clamp at the maternal end of the cord and allowing the blood in the placenta to flow outward. It is suggested that this method will make the placenta smaller and more compact by reducing its volume, thus providing more effective contractions in the uterus and consequently, earlier separation and expulsion of the placenta with less blood loss. This method is implemented as national policy in 32% of maternity units in Belgium, 24% in Portugal, 15% in Norway and Spain, and approximately 14% in Ireland. In our country, physicians and midwives have also been observed using this method when signs of placental separation are delayed. To facilitate placental separation, they open the clamp at the maternal end and allow some blood to flow from the placenta.
A review of studies reveals conflicting results. A Cochrane review of three studies involving 1,257 women reported that placental cord drainage shortened the length of the third stage of labor by an average of three minutes and reduced blood loss by an average of 77 ml. A meta-analysis of nine randomized controlled trials confirmed the effectiveness of placental cord drainage in shortening the length of the third stage, but the results showed that it did not reduce blood loss. However, more recent studies have reached conflicting conclusions. While some studies have found that placental cord drainage produces a significant reduction in postpartum blood loss and the duration of the third stage of labor, others have reported that it has no effect in reducing postpartum blood loss and shortening the third stage of labor. In addition, in all studies conducted on the subject, the incidence of complications such as postpartum hemorrhage, placental retention, hand hallas, additional medication and blood transfusion requirement was found to be lower. However, further studies are needed to determine whether placental cord drainage is effective in shortening the duration of the third stage of labor and reducing postpartum hemorrhage. Therefore, this study aimed to evaluate the effect of placental cord drainage on the third stage of labor and the amount of postpartum hemorrhage.
The study's results are significant because they add to the growing body of evidence by offering a new perspective on a controversial topic. The interventions implemented in this study are expected to result in a quicker delivery of the placenta, less bleeding, and a lower risk of postpartum complications. All of these benefits will contribute to a smoother delivery process. Complications experienced during the third stage can lead to anemia, necessitate blood transfusions, and delay the initiation of breastfeeding, affecting the health of the newborn. Considering the impact of all these negative effects on hospital costs, the national economy, and health indicators, it would be meaningful to expand the use of placental cord drainage in clinics for the active management of the third stage of labor, provided its effectiveness is demonstrated. Furthermore, considering its minimal effort, low cost, and its potential as an alternative midwifery method in regions where access to oxytocin and methergine is not available, widespread adoption is significant.
Data Collection
When pregnant women are admitted to the delivery room, the purpose, importance, and procedures of the study will be explained to those who meet the inclusion criteria. Written consent will be obtained from pregnant women who agree to participate. Pregnant women will then be assigned to either the intervention or control group based on their corresponding values in a simple random number table generated through www.random.org.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
盲法说明
Two groups with a intervention and control
入排标准
- 年龄范围
- 18 Years 至 35 Years(Adult)
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •No problem speaking and understanding Turkish
- •Low-risk pregnant women
- •Vertex presentation
- •37-41st weeks of gestation
- •There are no complications in the mother or the baby that prevent normal birth.
- •The VAS score for the pain felt by the pregnant woman at the time of admission to the study must be less than 3 (to show that the pregnant women were accepted into the study at a time when their pain was at its lowest and their decision-making ability was at a relatively good level)
排除标准
- •History of postpartum hemorrhage
- •History of postpartum hemorrhage in mother or sister
- •Birth interval less than 2 years
- •Anticoagulant use during pregnancy
- •Smoking during pregnancy
- •Those with low Hb values (Hb<11gr/dL)
- •Hematocrit <30
结局指标
主要结局
Determining the duration of the third stage of labor
时间窗: The time between the birth of the newborn and the delivery of the placenta
In the intervention and control groups, the time of placental delivery will be recorded using a digital clock. The time between the birth of the newborn and the delivery of the placenta will constitute the duration of the third stage of labor.
Determining the amount of blood lost in the 3rd stage
时间窗: Until one of the signs of placental separation is seen, maximum 5 minutes
In the control group, the blood collected in the V-drop (ml) will be measured and calculated. In the intervention group, the placental drainage blood collected in the kidney basin (grams) will be added to the blood collected in the V-drop (ml). The total amount of blood loss will be calculated in ml. The blood in the kidney basin will be calculated in ml as follows: (The weight of the kidney basin filled with blood after taring ÷ 1.05) (Asıcıoğlu et al, 2015).
Determination of the amount of hemorrhage at the 2nd hour postpartum
时间窗: Postpartum 0-2 hours
At the end of the second hour postpartum, the leak-proof underwear will be removed and weighed on a precision scale. The amount of blood lost at this stage will be calculated in ml as follows: (The weight of the leak-proof absorbent underwear used - the weight before use) ÷ 1.05. (Asıcıoglu et al, 2015).
次要结局
- Hemoglobin and hematocrit levels at 24 hours postpartum, changes compared to prepartum(Admission to the delivery room - postpartum 24th hour)
- The possibility of developing complications in the third stages of labor(The time from the moment of placental cord drainage until placental separation)
- The possibility of developing complications in the fourth stage of labor(Postpartum until the 24th hour after delivery of the placenta)
研究者
Sinem Gültekin
Sp. Midwife
Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
