Prospective Clinical Trial of Three Apical Sealing Materials
Phase 4
Completed
- Conditions
- Periapical Abscess
- Interventions
- Registration Number
- NCT04198298
- Lead Sponsor
- University of the Pacific
- Brief Summary
This prospective comparative randomized clinical trial compares healing and bony regeneration in patients who received 1 of 3 different retrograde filling materials following microsurgical apicoectomies for the treatment of periapical lesions of endodontic origin.
- Detailed Description
A prospective comparative randomized clinical trial was designed to evaluate the healing and bony regeneration in patients who received 1 of 3 different retrograde filling materials (EndoSequence®, ProRoot® MTA, or Biodentine®) following microsurgical apicoectomies for the treatment of periapical lesions of endodontic origin.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 59
Inclusion Criteria
- Adult patients, American Society of Anesthesiologists (ASA) classification I and II
- Any tooth with a single chronic periapical lesion requiring apical microsurgery
- Informed consent signed prior to surgery
Exclusion Criteria
- Background of drug/alcohol abuse
- Adjacent periapical lesion
- Periodontal disease
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Group 2 ProRoot MTA ProRoot MTA The ProRoot® MTA retrograde sealing material was used to provide a biologic seal at the apex. Group 3 Biodentine Biodentine The Biodentine® retrograde sealing material was used to provide a biologic seal at the apex. Group 1 EndoSequence EndoSequence The EndoSequence® retrograde sealing material was used to provide a biologic seal at the apex.
- Primary Outcome Measures
Name Time Method Rate of remineralization 6 months The pace at which new bone is redeposited
- Secondary Outcome Measures
Name Time Method