ACTRN12615000578505
Terminated
未知
Investigating the neurobiological and neurocognitive effects of combining cognitive training with tDCS following traumatic brain injury.
Dr Kate Hoy0 sites20 target enrollmentJune 3, 2015
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Traumatic Brain Injury (TBI)
- Sponsor
- Dr Kate Hoy
- Enrollment
- 20
- Status
- Terminated
- Last Updated
- 4 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Participants will be included if they: (1\) are aged 18\-65 and have capacity to consent; (2\) have experienced a closed head injury of mild to moderate severity determined by patient reports and hospital records of a loss of consciousness (LOC) of less than 24 hours, and an initial GCS of more than 9 ; (3\) are at least 6 weeks post injury to allow a degree a recovery from injuries sustained from the TBI prior to entering the trial; (4\) have an IQ of greater than 70 as determined by performance on the Wechsler Test of Adult Reading (WTAR) (to ensure they understand the study requirements) ; (5\) exhibit cognitive impairment, defined as a performance greater than 1 SD below published norms on any domain within the MATRICS.
Exclusion Criteria
- •Participants will be excluded if they (1\) have a diagnosis of a Psychiatric illness, lifetime (i.e. either pre or post TBI). In particular, as rTMS is known to effectively treat depression and this may impact upon the outcome variables, the presence of a depressive disorder (DSM 5 criteria) will exclude participation; (2\) have drug dependence or abuse; (3\) have a personal or family history of a seizure disorder; (4\) an unstable medical condition, neurological disorder, are currently pregnant or lactating; (5\) have metal in the cranium, a pacemaker, cochlear implant, medication pump or other electronic device.
Outcomes
Primary Outcomes
Not specified
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