MedPath

Enhancing Neonatal Sucking Reflex: A Study on the Efficacy of Magnesium Sulphate in Severe Birth Asphyxia

Not Applicable
Completed
Conditions
Birth Asphyxia
Interventions
Drug: Magnesium Sulphate infusion
Registration Number
NCT06468475
Lead Sponsor
RESnTEC, Institute of Research
Brief Summary

Children's Hospital Multan is a tertiary care teaching hospital in South Punjab, the poorest and most backward area of Punjab, Pakistan, where a significant number of newborns suffer from birth asphyxia. Therefore, this study was planned with the objective of investigating the effectiveness of magnesium sulphate in severe birth asphyxia, hypothesizing that in cases of birth asphyxia, neonates who are treated with magnesium sulphate have a higher sucking reflex than those who are not treated with magnesium sulphate.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
80
Inclusion Criteria
  • Full-term babies (≥37 weeks of gestation)
  • Both genders
  • Severe birth asphyxia
  • Admitted within six hours of life.
Exclusion Criteria
  • Premature babies
  • Congenital malformations
  • Babies born to mothers who received general anesthesia
  • Babies whose mothers received magnesium sulfate, pethidine, and other drugs in the past 7 days.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Magnesium Sulphate GroupMagnesium Sulphate infusion-
Primary Outcome Measures
NameTimeMethod
Efficacy72 hours

Efficacy was labeled as yes if the infant was placed in the supine position, the index finger was placed in the infant's mouth, and the power of sucking movements was judged after 5 seconds, and If the sucking reflex appeared. Efficacy was termed no otherwise.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

The Children's Hospital and the Institute of Child Health

🇵🇰

Multan, Punjab, Pakistan

© Copyright 2025. All Rights Reserved by MedPath