Stool surveillance in Pediatric blood and cancer related disorders and correlation with systemic infectio
- Conditions
- Health Condition 1: C81-C96- Malignant neoplasms of lymphoid, hematopoietic and related tissue
- Registration Number
- CTRI/2022/11/047624
- Lead Sponsor
- Manipal Academy of Higher Education
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
All children less than 18 years diagnosed in Pediatric Hematology and Oncology unit for the below mentioned indications and have consented for treatment on standardized institution treatment protocol:
1.Acute lymphoblastic Leukemia during intensive phase of chemotherapy
2.Acute myeloid leukemia during induction and consolidation chemotherapy
3.Lymphoblastic lymphoma undergoing intensive phase of chemotherapy
4.Burkitt lymphoma on intensive chemotherapy treated on LMB protocol
5.Patients undergoing bone marrow transplant
6.Relapsed acute lymphoblastic Leukemia during intensive phase of chemotherapy
1.Any child who has already been on treatment at a different centre
2.Any child who has a central line inserted at a different centre
3.Any child with solid tumor
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. To estimate the prevalence of MDRO colonisation in stool and CVAD in newly diagnosed children with cancer undergoing intensive chemotherapy at baseline (0 month and 6months)Timepoint: Baseline <br/ ><br> <br/ ><br>6 Months (End of intensive phase of chemotherapy) <br/ ><br>
- Secondary Outcome Measures
Name Time Method To evaluate the correlation between the MDRO colonisation with blood stream infections (baseline and 6months)Timepoint: Baseline <br/ ><br> <br/ ><br>At 6months