Effect of traditional 5-Fluorouracil emulsion versus smaller particles of 5-Fluorouracil emulsion in the treatment of skin aged by sun exposure and prone to developing Skin Cancer
- Conditions
- Skin Agingactinic keratosisC17.800.882
- Registration Number
- RBR-6w7vwb3
- Lead Sponsor
- Escola Paulista de Medicina/Universidade Federal de São Paulo - UNIFESP
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruitment completed
- Sex
- Not specified
- Target Recruitment
- Not specified
Male or female; over 50 years; phototypes I to III, according to Fitzpatrick Scale; forearms with clinical diagnosis of severe or advanced photoaging, associated with actinic keratosis; agreement to avoid photoexposure during the period of therapy; ability to understand and strictly respect the guidelines provided; availability for periodic visits
Smokers; including indirect smokers; or former smokers, who stopped smoking for at least two years; topical treatments with tretinoin less than six months and other retinoids, alphahydroxy acids, polyhydroxy acids, betahydroxy acids and ascorbic acid less than three months; treatment with superficial chemical peels; microdermabrasion and fractional lasers less than three months; oral retinoid less than six months; history of hypersensitivity to parabens; infectious or inflammatory dermatoses diagnosed on the arms; previous chemotherapy or radiotherapy treatment; clinical evidence of immunosuppression; presence or history of photodermatosis
Study & Design
- Study Type
- Intervention
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method