Vaginal Misoprostol and Foley Catheter for Late Second Trimester Termination of Pregnancy

Phase 2

Completed

• Conditions: Late Second Trimester Termination of Pregnancy
• Interventions: Drug: MisoprostoL; Device: Foley Catheter

• Registration Number: NCT02989324
• Lead Sponsor: Zagazig University

Brief Summary

Vaginal Misoprostol Versus Combined Low Dose Misoprostol Plus Foley Catheter for Late Second Trimester Termination of Pregnancy With Previous Multiple Cesarean Sections

Detailed Description

this study aims to compare between Vaginal Misoprostol and Combined Low Dose Misoprostol Plus Foley Catheter for Late Second Trimester Termination of Pregnancy With Previous Multiple Cesarean Sections to assess safety and efficacy of theses methods.

Study Timeline

• Study Start: 2016-01
• Status Verified: 2016-11
• Study First Submitted: 2016-11-30
• Study First Submitted QC: 2016-12-07
• Study First Posted: 2016-12-12
• Primary Completion: 2017-11
• Study Completion: 2017-11
• Last Update Submitted: 2018-02-06
• Last Update Posted: 2018-02-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 97

Inclusion Criteria

late second trimester

• IUFD
• Previous Multiple Cesarean Sections

Exclusion Criteria

Low lying placenta

• asthma
• allergy to misoprostol
• patient refuse to participate

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Misoprostol Plus Foley Catheter	Foley Catheter	Misoprostol Plus Foley Catheter for Late Second Trimester Termination of Pregnancy With Previous Multiple Cesarean Sections
Vaginal Misoprosto	MisoprostoL	Vaginal Misoprosto for Late Second Trimester Termination of Pregnancy With Previous Multiple Cesarean Section
Misoprostol Plus Foley Catheter	MisoprostoL	Misoprostol Plus Foley Catheter for Late Second Trimester Termination of Pregnancy With Previous Multiple Cesarean Sections

Primary Outcome Measures

Name	Time	Method
induction to expulsion interval	24 hours	from time to start induction to time of complete expulsion of product of conception

Trial Locations

Locations (1)

Zagazig University; 🇪🇬 Zagazig, Egypt