Staged Ureteroscopy After Initial Urinary Drainage Versus Direct Ureteroscopy in the Treatment of Pediatric Obstructive Calcular Anuria
试验速览
- 阶段
- 不适用
- 入组人数
- 50
- 试验地点
- 2
- 主要终点
- stone free status
研究概览
简要总结
To compare staged ureteroscopy following initial urinary drainage versus direct ureteroscopy without initial urinary drainage in the treatment of obstructive calcular anuria with acute renal failure in children.
详细描述
To compare staged ureteroscopy following initial urinary drainage and stabilization of renal functions using percutaneous nephrostomy or double J stent versus direct ureteroscopy without initial urinary drainage in the treatment of obstructive calcular anuria with acute renal failure due to ureteric calculi in children.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- — 至 12 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •children ≤12 years old presenting with Obstructive Anuria and Acute Renal Failure due to bilateral ureteric stones suitable for ureteroscopy.
排除标准
- •Fever, pyonephrosis or sepsis.
- •unstable patients are stabilized first by dialysis.
研究组 & 干预措施
initial urinary drainage
initial urinary drainage to stabilize renal functions before ureteroscopy
干预措施: initial urinary drainage (Procedure)
direct ureteroscopy
direct ureteroscopy without initial urinary drainage
干预措施: direct ureteroscopy (Procedure)
结局指标
主要结局
stone free status
时间窗: 1 week
success in removal of ureteric stones using ureteroscopy
Return to normal creatinine
时间窗: 1 week
period for return to normal creatinine in both groups
operative and early post operative complications
时间窗: 1 week
Hematuria, Extravasation (perforation), mucosal complications, stone migration, failure of ureteric access, fever
次要结局
- ureteric stricture(6 months)
- period to reach stone free status bilaterally(6 months)
- number of times of exposure to general anesthesia(6 months)
研究者
mohammed said elsheemy
Associte professor of urology
Cairo University