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Evaluation of the effects of two weeks wear of silicone hydrogel lenses used with one of two lens disinfection solutions on the surface of the eye.

Not Applicable
Completed
Conditions
Contact Lens Wear
Eye - Normal eye development and function
Registration Number
ACTRN12609000568213
Lead Sponsor
niversity of New South Wales
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
50
Inclusion Criteria

Suitability to contact lens wear and ability to be corrected with the range of contact lens powers and base curves available from the manufacturer.

Exclusion Criteria

Contraindications to contact lens wear.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
To assess ocular surface changes after contact lens wear. Measurements will include tear secretion rate using Phenol red thread test, tear osmolarity using a vapor pressure osmometer, tear fluorescein break-up time, ocular surface staining and number of goblet cells using impression cytology for the conjunctival surface.[Baseline, 1 day, 1 week, 2 week and after 1 week recovery]
Secondary Outcome Measures
NameTimeMethod
To correlate ocular surface changes with subjective symptoms. Standardised questionnaires (McMonnies questionnaire, ocular symptoms questionnaires) will be used to assess subjective symptoms.[Baseline, 1 day, 1 week, 2 week and after 1 week recovery]
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