Tick Test & Prophylaxis Proof.

Completed

• Conditions: yme disease (Lyme ziekte)tick bite (tekenbeet)prophylaxis (profylaxe)antibiotics (antibiotica)

• Registration Number: NL-OMON27133
• Lead Sponsor: RIVM

Brief Summary

/A

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 2500

Inclusion Criteria

1. 8 yrs and older;

2. Not pregnant;

Exclusion Criteria

1. Not able to give informed consent or do not have a thorough command of the Dutch language;

2. Report other tick bites in the three months before inclusion;

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Efficacy of prophylaxis, i.e. the relative risk (RR) reduction for developing Lyme disease after a tick bite and the Number Needed to Treat (NNT) to prevent one case of Lyme disease. The tick screening results will be used to assess the reduction in NNT when only prescribing prophylaxis if the tick is infected and the engorgement or<br>attachment time are above a certain threshold.

Secondary Outcome Measures

Name	Time	Method
The number of participants that develop Adverse Events in the month after taking the prophylaxis. <br>Scores for epidemiological risk factors for acquiring tick bites and developing Lyme disease such as exposure to ticks in daily life, participants’ activities when acquiring the tick bite, area of acquiring the tick bite, prevention of tick bites. <br>Differences in NNT for children and adults.