To compare the pain reliving efficacy of two pain relieving medicines in postsurgery in pain patients coming for lower spine surgeries - due to spinal cord compressio
Not Applicable
Completed
- Conditions
- Health Condition 1: G55- Nerve root and plexus compressionsin diseases classified elsewhere
- Registration Number
- CTRI/2019/08/020573
- Lead Sponsor
- Institutional Review Board
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 50
Inclusion Criteria
1. ASA I AND II
2. Patients Undergoing Lumbar Laminectomy And Discectomy Surgery
3. Normal Renal Functions
Exclusion Criteria
1. ASA III OR IV
2. BMI >40
3. Impaired Renal Function
4. Intraoperative CSF Leak
5. Any Contraindications to Morphine and Ketamine
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Time Taken to Receive First Rescue AnalgesiaTimepoint: 3 Hours
- Secondary Outcome Measures
Name Time Method 1. NRS score 1-10 <br/ ><br>2. Total Amount of Rescue Analgesic Consumed: Cumulative opioid Consumption <br/ ><br>3. Post OP Haemodynamics : HR , BP , RR , sedation <br/ ><br>4. Post OP Complications - Vomiting , Pruritis , urinary retention , Respiratory depression <br/ ><br>Timepoint: 24 Hours
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What are the molecular mechanisms by which epidural morphine and ketamine provide analgesia in spinal cord compression post-surgery?
How does the combination of epidural morphine with ketamine compare to morphine alone in managing postoperative pain after lumbar laminectomy and discectomy?
Are there specific biomarkers that can predict patient response to epidural morphine or ketamine in post-lumbar surgery pain management?
What are the potential adverse events associated with epidural administration of morphine and ketamine in spinal cord compression patients?
What other analgesic agents or combination therapies are being explored for postoperative pain relief in spinal cord compression surgeries?