Evaluation of the Updated Procedure for the Management of Refractory Out-of-hospital Cardiac Arrests with SAMU 54 : the Revised ACEP Protocol in 02/2024
Trial Snapshot
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Sponsor
- Enrollment
- 150
- Locations
- 1
- Primary Endpoint
- Survival
Study Overview
Brief Summary
ECPR is a technique that has been rapidly developed in many cardiac arrest specialized centers In 2013, a specific management protocol was developed for patients in refractory out-of-hospital cardiac arrest around Nancy, France. To select patients with the best prognosis, the inclusion criteria defined were strict. This led to an over-selection of patients and a significant reduction in the number of eligible patients. A balance needed to be struck between over-selecting patients and maintaining the expertise of medical and paramedical teams in the field. In addition, it has also been shown that ECPR also increases the number of organs and transplants.
In February 2024, the criteria for inclusion in the protocol were redefined to include any witnessed non-traumatic cardiac arrest, whatever the initial rhythm. This simplification should enable more patients to be included in the procedure.
The aim of the study is to assess the patient's outcome
Study Design
- Study Type
- Observational
- Observational Model
- Case Only
- Time Perspective
- Retrospective
Eligibility Criteria
- Ages
- 18 Years to 65 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Out-of-hospital cardiac arrest
- •enrolled in the ECPR program
- •18 years old or more
- •Low-flow estimated <60minutes
Exclusion Criteria
- •traumatic cardiac arrest
- •major comorbidities
Outcomes
Primary Outcomes
Survival
Time Frame: 90 days after cardiac arrest
Survival rate of patients enrolled in the protocol
Secondary Outcomes
- Delays(From event to implementation of ECMO, in minutes, Up to 180 minutes)
- Neurological outcome(30 days and 90 days after cardiac arrest)
Investigators
JAEGER Deborah
Principal investigator
Central Hospital, Nancy, France