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Clinical Trials/NCT06603649
NCT06603649Not yet recruitingNot Applicable

Evaluation of the Updated Procedure for the Management of Refractory Out-of-hospital Cardiac Arrests with SAMU 54 : the Revised ACEP Protocol in 02/2024

Central Hospital, Nancy, France1 site in 1 country150 target enrollmentStarted: October 1, 2024Last updated:
Conditions

Trial Snapshot

Phase
Not Applicable
Status
Not yet recruiting
Sponsor
Enrollment
150
Locations
1
Primary Endpoint
Survival

Study Overview

Brief Summary

ECPR is a technique that has been rapidly developed in many cardiac arrest specialized centers In 2013, a specific management protocol was developed for patients in refractory out-of-hospital cardiac arrest around Nancy, France. To select patients with the best prognosis, the inclusion criteria defined were strict. This led to an over-selection of patients and a significant reduction in the number of eligible patients. A balance needed to be struck between over-selecting patients and maintaining the expertise of medical and paramedical teams in the field. In addition, it has also been shown that ECPR also increases the number of organs and transplants.

In February 2024, the criteria for inclusion in the protocol were redefined to include any witnessed non-traumatic cardiac arrest, whatever the initial rhythm. This simplification should enable more patients to be included in the procedure.

The aim of the study is to assess the patient's outcome

Study Design

Study Type
Observational
Observational Model
Case Only
Time Perspective
Retrospective

Eligibility Criteria

Ages
18 Years to 65 Years (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Out-of-hospital cardiac arrest
  • enrolled in the ECPR program
  • 18 years old or more
  • Low-flow estimated <60minutes

Exclusion Criteria

  • traumatic cardiac arrest
  • major comorbidities

Outcomes

Primary Outcomes

Survival

Time Frame: 90 days after cardiac arrest

Survival rate of patients enrolled in the protocol

Secondary Outcomes

  • Delays(From event to implementation of ECMO, in minutes, Up to 180 minutes)
  • Neurological outcome(30 days and 90 days after cardiac arrest)

Investigators

Sponsor
Central Hospital, Nancy, France
Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

JAEGER Deborah

Principal investigator

Central Hospital, Nancy, France

Study Sites (1)

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