Study to evaluate factors associated with maximum mouth opening in patients with squamous cell carcinoma. of oral cavity and oropharynx
Not Applicable
- Conditions
- Health Condition 1: null- Squamous Cell Carcinoma of oral cavity or oropharynx
- Registration Number
- CTRI/2011/11/002106
- Lead Sponsor
- Tata Memorial Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 120
Inclusion Criteria
1)Patients with age of 18 years or more.
2)Patients with biopsy proven squamous cell cancer (SCC) of oral cavity or oropharynx,
3)Patients planned for surgery for SCC of oral cavity or oropharynx.
4)Patients planned for curative radiotherapy to face and neck.
5)Patients planned for post operative radiotherapy to face and neck.
6)Patients who have received 50Gy of radiation or more to face and neck.
Exclusion Criteria
1)Any previous treatment for cancer in the region of head and neck.
2)Patients with history of previous trauma, tetanus, temporo-mandibular disorder, or oral submucous fibrosis which may contribute to trismus.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Correlation between maximum mouth opening, tumor and treatment related factors in patients with SCC of oral cavity or oropharynx.Timepoint: Maximum mouth opening will be measured before treatment,after surgery, before radiation therapy, after radiation therapy and 6,12,18 and 24 months follow up.
- Secondary Outcome Measures
Name Time Method Co-relation between maximum mouth opening and dental caries index in patients with SCC of oral cavity or oropharynx.Timepoint: Maximum mouth opening will be measured before treatment,after surgery, before radiation therapy, after radiation therapy and 6,12,18 and 24 months follow up.;Co-relation between maximum mouth opening and quality of life (using EORTC questionnaire) in patients with SCC of oral cavity and oropharynxTimepoint: Maximum mouth opening will be measured before treatment,after surgery, before radiation therapy, after radiation therapy and 6,12,18 and 24 months follow up.