Correlation Between Intraoperative Electroencephalographic Signatures and Postoperative Delirium in Preoperative Frail Elderly Patients Undergoing
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 66
- 试验地点
- 1
- 主要终点
- The number of minutes of suppression assessed by visual analysis of the EEG
研究概览
简要总结
The goal of this [type of study: observational study ] is to [compare Energy differences in various bands of intraoperative electroencephalogram in elderly patients with postoperative delirium and non delirium.] in [describe participant population selected 69 patients who underwent laparoscopic radical surgery for colorectal cancer on a selective basis]. The main question[s] it aims to answer are:
• [Is there any difference in the spectral range of EEG between POD patients and non POD patients] Participants will [Cognitive.•Postoperative delirium.•Preoperative weakness.]
详细描述
The goal of this [type of study: observational study ] is to [compare Correlation between EEG data and postoperative delirium in elderly patients undergoing colorectal cancer radical surgery under preoperative frailty monitoring.] in [describe participant population selected 69 patients who underwent laparoscopic radical surgery for colorectal cancer on a selective basis]. The main question[s] it aims to answer are:
• [Is there any difference in the spectral range of EEG between POD patients and non POD patients] Participants will [Sedline EEG monitoring electrodes were placed 1cm above the eyebrows on both sides of the patient and at the temples on both sides, and were continuously monitored from the start of anesthesia in the operating room until the end of the surgery.Pay close attention to the vital signs and wait for the patient to fully recover and the vital signs to basically return to the preoperative level before returning to the ward.•Assessment of cognitive function using the Mini Mental State Scale (MMSE) 1 day before surgery and 7 days after surgery.•Preoperative assessment of frailty using the frailty screening scale.•Assess delirium using the ICU Patient Ambiguity Assessment Form (CAM-ICU) 1 day, 2 days, 3 days, and 7 days after surgery.].
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 65 Years 至 90 Years（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •ASA I-III
- •The preoperative Frailty Scale (FRAIL) assessed frailty
- •The patient or his/her family is informed about the study and signs an informed consent form
排除标准
- •Serious insufficiency of heart, liver, kidney and other functions
- •Those with a history of psychiatric or neurological illness, long-term use of psychotropic drug
- •History of cerebrovascular disease, brain trauma, or surgery
- •The patient was allergic to coupler or unable to place electrodes on the head
- •The patient was unable to complete the scale assessment as required.Patients with severe attention to hearing impairment were unable to complete the interview
- •The patient was diagnosed with delirium before surgery
结局指标
主要结局
The number of minutes of suppression assessed by visual analysis of the EEG
时间窗: Throughout the operation
The burst suppression time was calculated by EEG visual analysis
EEG power of each band
时间窗: During the procedure
Recording frontal lobe electroencephalogram using a sedline root monitor (Masimo, Crop)
Postoperative delirium
时间窗: 1 day, 2 days, 3 days, and 7 days after surgery
Assessing delirium using the ICU Patient Ambiguity Assessment Form (CAM-ICU)
次要结局
未报告次要终点
研究者
Zhuo Liu
Principal Investigator
The First Hospital of Qinhuangdao