Cognitive and Electrophysiological Assessment of Non-Invasive Temporally-Interfering Electric Fields Stimulation (TIEFS)
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 15
- 试验地点
- 1
研究概览
简要总结
The goal of this clinical trial is to learn how a non-invasive brain stimulation method called Temporally Interfering Electric Fields Stimulation (TIEFS) affects brain activity and thinking in adults. TIEFS uses electrical currents applied to the scalp to influence brain activity without surgery.
The main questions this study aims to answer are:
- How does TIEFS change brain signals measured with brain recordings?
- Does TIEFS affect thinking abilities such as memory, language, movement, or perception?
- Is TIEFS safe and well tolerated when used in people?
This study includes two groups of participants. One group includes adults with epilepsy who are already undergoing specialized brain monitoring as part of their medical care. The other group includes healthy adults with no history of seizures.
Participants will:
- Receive brief sessions of TIEFS using electrodes placed on the scalp
- Complete computer-based tasks that test memory, attention, language, or movement. Answer questions about how the stimulation feels
- Have brain activity recorded during the study
Each study visit lasts up to three hours and may occur in one or two sessions. Information from this study may help researchers better understand the human brain and support the development of future non-invasive brain stimulation treatments.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Sequential
- 主要目的
- Basic Science
- 盲法
- Single (Participant)
盲法说明
Participants are masked to the type of stimulation they receive. They are not told whether the stimulation delivered during a session is active or sham. Researchers and study staff are aware of the stimulation type, and no other parties are masked in this clinical trial.
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Adult patients (age 18-65 years of age) undergoing an intracerebral electrophysiology study for epilepsy pre-surgical evaluation are eligible for inclusion.
- •For healthy control subjects are also eligible for inclusion (Scalp EEG measurements).
- •Participants must be able to sufficiently speak and understand English or Spanish for consent and be able to understand and complete cognitive tasks.
- •All subjects must have the ability to give valid informed consent.
排除标准
- •No pregnant women will be recruited.
- •People with implanted electrical devices such as Deep Brain Stimulation devices or Pacemakers.
- •No prisoners will be recruited.