Systematic Pelvic Lymphadenectomy Versus no Lymphadenectomy in Clinical Stage I-II Endometrial Cancer
Not Applicable
Completed
- Conditions
- Endometrial Cancer
- Registration Number
- NCT00482300
- Lead Sponsor
- University of Roma La Sapienza
- Brief Summary
The purpose of this trial is to determine whether the addition of systematic pelvic lymphadenectomy to hysterectomy with bilateral adnexectomy improves disease-free survival (DFS) and overall survival (OS) in patients with preoperatively supposed Stage I-II endometrial cancer
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- Not specified
Inclusion Criteria
- Histologically proven endometrioid or adenosquamous endometrial carcinoma.
- Patients having myometrial invasion
- Age =/< 75 years
- Informed consent.
Exclusion Criteria
- Serous papillary and clear cell tumors.
- Karnofsky index < 80 or severe diseases contraindicating surgery
- Concomitant neoplasia (basalioma cutis excluded)
- Distant metastasis or abdominal metastasis detected intraoperatively.
- Absence of myometrial invasion at frozen section.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method