The effect of Neuromuscular Electrical Stimulation on post-prandial muscle protein accretion in healthy elderly me
Completed
- Conditions
- muscle metabolismdisuse atrophy1003700810028302
- Registration Number
- NL-OMON36866
- Lead Sponsor
- niversiteit Maastricht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 12
Inclusion Criteria
Male
Age 65 - 85 years
18.5 < BMI < 30 kg*m2
Exclusion Criteria
- Type II diabetes
- All co morbidities interacting with mobility and muscle metabolism of the lower limbs (e.g. arthrosis, arthritis, spasticity/rigidity, all neurological disorders and paralysis).
- Use of anticoagulants, blood diseases, allergy for lidocain
- Use of NSAIDs and acetylsalicylic acid
- Patients suffering from PKU (Phenylketonuria)
- Presence of implantable cardioverter defibrillator and/or pacemaker
- Performed regular resistance type exercise in the past 6 months
- Use of any tools to assist during walking (cane/ crutches/ walker)
- (Partial) foot/ leg amputation
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Muscle protein synthesis rates, expressed as fractional synthetic rate (FSR).</p><br>
- Secondary Outcome Measures
Name Time Method <p>Muscle tracer enrichment, digestion and absorption kinetics of a casein drink<br /><br>influenced by NMES.</p><br>