Evaluation of role of MRI and CT scan in the internal radiotherapy of cervical cancer for the precise delivery of treatment.
Not Applicable
- Conditions
- Health Condition 1: C538- Malignant neoplasm of overlappingsites of cervix uteri
- Registration Number
- CTRI/2019/01/016911
- Lead Sponsor
- Dr Ram Manohar Lohia Institute of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Age between 25 and 60 years.
Histologically proven squamous carcinoma of the uterine cervix of FIGO stage IIA to IIIB.
Patient must have completed EBRT.
Patient willing to sign the informed consent.
Patient should be compatible for MRI pelvis. (No metallic or implant of ferromagnetic substance)
KPS > 70
Patient should be fit for General anesthesia (GA) with normal renal function.
Exclusion Criteria
Stage IV disease
Para-aortic nodes +ve
History of any other malignancy within the last 5 years
Adenocarcinoma of the cervix
Patient suffering from active HIV, Hepatitis B or C.
Pregnancy or lactating women
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Comparison of volumetric doses of target volume and dose volume histogram parameters of organ at risks (rectum, bladder, sigmoid and urethra) achieved with MRI vis-Ã -vis CT based plansTimepoint: 2 years
- Secondary Outcome Measures
Name Time Method To evaluate for acute toxicities (gastrointestinal, genitourinary and vaginal) and loco-regional control ratesTimepoint: At 6 months and 1 year