Investigating the Relationship Between Haemorrhoids, Internal Iliac Veins and Tributary Reflux
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 57
- 试验地点
- 1
- 主要终点
- Reflux in ovarian veins
研究概览
简要总结
This case series aims to find out in a group of female patients suffering from haemorrhoids, how many of them have pelvic vein reflux that feeds into their haemorrhoids.
This will be done by examining their ovarian and internal iliac veins for reflux, using a transvaginal scan.
详细描述
Based on previous research, we believe that haemorrhoids could be caused by faulty valves in the veins running from deep within the pelvic region to the lower part of the abdomen (internal iliac veins)resulting in reflux in the tributaries.
We have already presented research showing that patients with severe pelvic vein reflux, particularly of the internal iliac veins and tributaries, are associated with a higher chance of haemorrhoids.
The aim of this study is to see in a group of patients suffering from haemorrhoids, whether all of them exhibit pelvic vein reflux feeding into the haemorrhoids.
If we are able to prove that either all or the vast majority of patients with true haemorrhoids do have pelvic vein reflux feeding into them, this will support our hypothesis that the internal iliac vein and tributary reflux is causative of haemorrhoids.
following this, in a future study we will treat internal iliac vein and tributary reflux to see if the results of haemorrhoid treatments are improved.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Symptomatic haemorrhoids
- •Being able and willing to undergo transvaginal ultrasound scan to assess their ovarian and internal iliac veins
- •Aged between 18 and 80 years
- •good understanding of written and spoken english
排除标准
- •aged younger than 18 or older than 80
- •Those unwilling to attend for a transvaginal scan at The Whiteley Clinic, Guildford
结局指标
主要结局
Reflux in ovarian veins
时间窗: Immediatley
Following a transvaginal scan pelvic reflux in both the right and left leg separately will be rated on a four point scale 0 no reflux 1. trickle reflux 2. significant reflux 3. severe reflux
次要结局
未报告次要终点