Insulin and Standard Management in Hypertriglyceridemic Acute Pancreatitis

Phase 4

Not yet recruiting

• Conditions: Hypertriglyceridemia; Acute Pancreatitis
• Interventions: Biological: insulin; Other: standard treatment

• Registration Number: NCT05487833
• Lead Sponsor: University Medical Centre Ljubljana

Brief Summary

To compare the efficacy of infusion containing insulin and infusion without insulin on reduction of triglycerides in acute hypertriglyceridemic pancreatitis

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2022-04-06
• Study First Submitted QC: 2022-08-03
• Study First Posted: 2022-08-04
• Status Verified: 2022-10
• Last Update Submitted: 2022-10-31
• Study Start: 2022-11
• Last Update Posted: 2022-11-01
• Primary Completion: 2024-09
• Study Completion: 2024-09

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• acute pancreatitis
• triglycerides > 15 mmol/l

Exclusion Criteria

• diabetes on peroral therapy or insulin
• blood glucose > 11 mmol/l
• pregnancy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
insulin	insulin	-
standard management	standard treatment	-

Primary Outcome Measures

Name	Time	Method
%triglyceride reduction	after 18 hours of treatment	change in triglycerides, expressed as % of initial value

Secondary Outcome Measures

Name	Time	Method
incidence of hypoglycemia	during treatment with insulin, up to day 5