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Clinical Trials/NCT05487833
NCT05487833
Not yet recruiting
Phase 4

Comparison of Insulin and Standard Management in Hypertriglyceridemic Acute Pancreatitis in Patients Without Diabetes

University Medical Centre Ljubljana0 sites30 target enrollmentStarted: November 2022Last updated:
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ConditionsHypertriglyceridemiaAcute Pancreatitis

Overview

Phase
Phase 4
Status
Not yet recruiting
Enrollment
30
Primary Endpoint
%triglyceride reduction
OverviewStudy DesignEligibility CriteriaOutcomesInvestigatorsRecords & IdentifiersSimilar Trials

Overview

Brief Summary

To compare the efficacy of infusion containing insulin and infusion without insulin on reduction of triglycerides in acute hypertriglyceridemic pancreatitis

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Crossover
Primary Purpose
Treatment
Masking
None

Eligibility Criteria

Ages
18 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • •acute pancreatitis
  • •triglycerides \> 15 mmol/l

Exclusion Criteria

  • •diabetes on peroral therapy or insulin
  • •blood glucose \> 11 mmol/l
  • •pregnancy

Outcomes

Primary Outcomes

%triglyceride reduction

Time Frame: after 18 hours of treatment

change in triglycerides, expressed as % of initial value

Secondary Outcomes

  • incidence of hypoglycemia(during treatment with insulin, up to day 5)

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Jakob Gubensek

Principal investigator

University Medical Centre Ljubljana

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