The effect of cognitive behaviour therapy on central activation failure in Chronic Fatigue Syndrome

• Conditions: chronisch vermoeidheidssyndroom; Chronic fatigue; Chronic fatigue syndrome

• Registration Number: NL-OMON33070
• Lead Sponsor: niversitair Medisch Centrum Sint Radboud

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 30

Inclusion Criteria

- CDC-criteria for CFS
- starting cognitive behaviour therapy
- female

Exclusion Criteria

- self-reported functional limitations of the arm or schoulder

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Slope of Central Activation Failure (CAF) , Muscle Fibre Conduction Velocity<br /><br>(MFCV) and Maximal Voluntary Force (MVF) during the two-minute MVC before and<br /><br>after CBT.<br /><br>Successful therapy, defined as a score on the subscale fatigue of the CIS <35<br /><br>and a total score on the SIP < 700</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Slope of the MVF during the two minute MVC before and after CBT. MVF is the<br /><br>Maximal Voluntary Force (N) of the m. biceps brachii.<br /><br>Slope of the MFCV during the two minute MVC before and after CBT: MFCV is the<br /><br>Muscle Fibre Conduction Velocity (m/s) of the nerve to the m. biceps brachii.<br /><br>(sidebranch n. musculocutaneus)</p><br>