Validity of Cow's Milk-related Symptom Score Among Children Suspected to Have Cow's Milk Protein Alergy

Recruiting

Interventions: Other: stool analysis , CBC, specific IgE FOR Cow milk protein allergy

Brief Summary: Cow's milk protein allergy is a sensitivity reaction against cow's milk protein and and is calcified as IgE-medaited, non- IgE mediated and mixed type according to the underlying immunological mechanism.

Cow's Milk related Symptom Score ( CoMiSS) Considers general manifestation and dermatological, gastrointestinal and respiratory symptoms.

Recruitment & Eligibility

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Arm && Interventions

Group	Intervention	Description
patient with cow milk protein allergy	stool analysis , CBC, specific IgE FOR Cow milk protein allergy	apply CoMiSS on patient suspected to have cow milk protein allergy.

Primary Outcome Measures

Name	Time	Method
patient who are diagnosed as cow milk protein allergy by CoMiss	one year	measure the accuracy percentage (%) of the Cow's milk-related symptoms score in diagnosis of cow milk allergy at pediatrics department in Sohag hospital university
interpretation of the Cow's milk-related symptoms score	one year	The scoring ranges from 0 to 33. Each symptom has a maximal score of 6, except respiratory symptoms where the maximal score is 3. * If final score \> 12, the symptoms are likely cow's milk related. This could potentially be CMPA. * If final score \< 12, the symptoms are less likely related to cow's milk. Look for other causes. * CMPA diagnosis can only be confirmed by an elimination diet followed by an oral food challenge.
Food Challenge Test	one year	positive or negative Food Challenge Test

Secondary Outcome Measures

Name	Time	Method

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