Classification of Dysphagia Patients at Risk of Aspiration Pneumonia Using Machine Learning Algorithms Incorporating Acoustic Features From Phonetic Evaluation
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 449
- 试验地点
- 1
- 主要终点
- Functional Oral Intake Scale
研究概览
简要总结
In this prospective study we extracted acoustic parameters using PRAAT from patient's attempt to phonate during the clinical evaluation using a digital smart device. From these parameters we attempted (1) to define which of the PRAAT acoustic features best help to discriminate patients with dysphagia (2) to develop algorithms using sophisticated ML techniques that best classify those i) with dysphagia and those ii ) at high risk of respiratory complications due to poor cough force.
详细描述
This study was prospective study, and patients who visited the department of rehabilitation medicine in a single university-affiliated tertiary hospital with dysphagic symptoms from September 2019 to March 2021 were included.Voice recording was performed at the enrollment with blinded assessment, where the participants first visited the rehabilitation department with chief complaints of dysphagia. The cough sounds were recorded with an iPad (Apple, Cupertino, CA, USA) through an embedded microphone.
From the acoustic files we extracted fourteen voice parameters that include the average value and standard deviation of the fundamental frequency (f0), harmonic-to-noise ratio (HNR), the jitter that refers to frequency instability, and the shimmer that represents the amplitude instability of the sound signal.
Machine learning algorithms and sophisticated deep neural network analysis will be performed.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 19 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Inclusion criteria
- •Suspected swallowing disorder who were referred for swallowing assessment
- •Dysphagia attributable to brain lesion including stroke
排除标准
- •Participants who were unable to perform phonation
- •Participants who had no VFSS or standardized swallowing assessment results
- •Participants with no spirometric measurements
结局指标
主要结局
Functional Oral Intake Scale
时间窗: during the intervention
Dysphagia severity as measured by the the Functional Oral Intake Scale obtained from standardized swallowing tests
Cough strength
时间窗: during the intervention
Spirometry values : cough strength as measured by the spirometric values during voluntary cough
次要结局
未报告次要终点
研究者
Sun Im
associate professor
The Catholic University of Korea