Classification of Dysphagia Patients at Risk of Aspiration Pneumonia Using Machine Learning Algorithms Incorporating Acoustic Features From Phonetic Evaluation
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Respiration Disorders
- Sponsor
- The Catholic University of Korea
- Enrollment
- 449
- Locations
- 1
- Primary Endpoint
- Functional Oral Intake Scale
- Status
- Completed
- Last Updated
- 4 years ago
Overview
Brief Summary
In this prospective study we extracted acoustic parameters using PRAAT from patient's attempt to phonate during the clinical evaluation using a digital smart device. From these parameters we attempted (1) to define which of the PRAAT acoustic features best help to discriminate patients with dysphagia (2) to develop algorithms using sophisticated ML techniques that best classify those i) with dysphagia and those ii ) at high risk of respiratory complications due to poor cough force.
Detailed Description
This study was prospective study, and patients who visited the department of rehabilitation medicine in a single university-affiliated tertiary hospital with dysphagic symptoms from September 2019 to March 2021 were included.Voice recording was performed at the enrollment with blinded assessment, where the participants first visited the rehabilitation department with chief complaints of dysphagia. The cough sounds were recorded with an iPad (Apple, Cupertino, CA, USA) through an embedded microphone. From the acoustic files we extracted fourteen voice parameters that include the average value and standard deviation of the fundamental frequency (f0), harmonic-to-noise ratio (HNR), the jitter that refers to frequency instability, and the shimmer that represents the amplitude instability of the sound signal. Machine learning algorithms and sophisticated deep neural network analysis will be performed.
Investigators
Sun Im
associate professor
The Catholic University of Korea
Eligibility Criteria
Inclusion Criteria
- •Inclusion criteria
- •Suspected swallowing disorder who were referred for swallowing assessment
- •Dysphagia attributable to brain lesion including stroke
Exclusion Criteria
- •Participants who were unable to perform phonation
- •Participants who had no VFSS or standardized swallowing assessment results
- •Participants with no spirometric measurements
Outcomes
Primary Outcomes
Functional Oral Intake Scale
Time Frame: during the intervention
Dysphagia severity as measured by the the Functional Oral Intake Scale obtained from standardized swallowing tests
Cough strength
Time Frame: during the intervention
Spirometry values : cough strength as measured by the spirometric values during voluntary cough