The effect of trehalose supplementation on stroke patients
- Conditions
- Critically ill stroke patients hospitalized in ICU.
- Registration Number
- IRCT20201129049534N9
- Lead Sponsor
- Esfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 80
Willingness to cooperate and sign the consent form by the patient or the patient's legal guardian
Diagnosis of stroke by a specialist doctor and hospitalization in the intensive care unit (ICU)
Age 18 to 80 years
Stable hemodynamic and metabolic conditions in the first 24 to 48 hours
Having enteral nutrition
Not having food intolerance to food sources containing trehalose such as mushrooms
Glasgow Coma Scale (GCS) =3
Having a history of cancer, autoimmune diseases, congenital metabolic diseases, underlying heart disease, kidney failure, liver failure and pancreatitis
Patients who have cancer and are undergoing chemotherapy treatment.
Pregnancy and breastfeeding.
Impossibility of enteral nutrition in the first 48 hours of admission.
Patients who are hospitalized in the intensive care unit for less than 48 hours.
Patients undergoing dialysis.
Patients who do not have an indication for enteral nutrition on the first day, and based on the diagnosis of the special care department, it is confirmed and predicted that they will not be able to receive enteral nutrition in the future. (nausea, persistent vomiting, ileus, intestinal obstruction, uncontrolled diarrhea (>500 mL/day), high-output fistula (>500 mL/day), intestinal inaccessibility, incomplete resuscitation, and hemodynamic instability.
Patients who are under nutritional support by total intravenous nutrition.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method