Specific Methylation Profiles in HNSCC

Recruiting

• Conditions: Head and Neck Squamous Cell Carcinoma

• Registration Number: NCT04567056
• Lead Sponsor: Aalborg University Hospital

Brief Summary

In the study, N-20190047, the investigators aim to define specific methylation patterns in a group of patients with head and neck squamous cell carcinomas.

With this study the investigators aim to validate these findings in a larger cohort.

Detailed Description

Not available

Study Timeline

• Study Start: 2020-09-16
• Study First Submitted: 2020-09-23
• Study First Submitted QC: 2020-09-23
• Study First Posted: 2020-09-28
• Status Verified: 2025-02
• Last Update Submitted: 2025-02-05
• Last Update Posted: 2025-02-07
• Primary Completion: 2025-12-31
• Study Completion: 2026-06-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 300

Inclusion Criteria

• Written informed consent
• Verified head and neck squamous cell carcinoma

Exclusion Criteria

• Other active cancer
• Uncontrolled comorbidity
• Unable to give informed consent

Control group:

Inclusion Criteria:

• Written informed consent
• Normal ENT-examination

Exclusion Criteria:

• Other active cancer
• Uncontrolled comorbidity
• Unable to give informed consent

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Diagnostic accuracy	At diagnosis	How accurate can the methylation profiles diagnose the head and neck squamous cell carcinoma

Trial Locations

Locations (1)

Department of Otolaryngology - Head and Neck Surgery; 🇩🇰 Aalborg, Denmark