Specific Methylation Profiles in HNSCC
Recruiting
- Conditions
- Head and Neck Squamous Cell Carcinoma
- Interventions
- Diagnostic Test: Blood sample
- Registration Number
- NCT04567056
- Lead Sponsor
- Aalborg University Hospital
- Brief Summary
In the study, N-20190047, the investigators aim to define specific methylation patterns in a group of patients with head and neck squamous cell carcinomas.
With this study the investigators aim to validate these findings in a larger cohort.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 300
Inclusion Criteria
- Written informed consent
- Verified head and neck squamous cell carcinoma
Exclusion Criteria
- Other active cancer
- Uncontrolled comorbidity
- Unable to give informed consent
Control group:
Inclusion Criteria:
- Written informed consent
- Normal ENT-examination
Exclusion Criteria:
- Other active cancer
- Uncontrolled comorbidity
- Unable to give informed consent
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Cancer group Blood sample Patients with verified head and neck squamous cell carcinomas Control group Blood sample Matched control group without active or earlier cancer and a normal ENT examination.
- Primary Outcome Measures
Name Time Method Diagnostic accuracy At diagnosis How accurate can the methylation profiles diagnose the head and neck squamous cell carcinoma
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Department of Otolaryngology - Head and Neck Surgery
🇩🇰Aalborg, Denmark