Impact of Perioperative Anemia and Red Blood Cells Transfusion on Post-operative Complications After Oncological Surgery
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Anemia
- Sponsor
- University Hospital, Brest
- Enrollment
- 300
- Locations
- 1
- Primary Endpoint
- Number of mortality or any respiratory, cardiac, renal, thromboembolic, infectious and/or hemorrhagic post operative complications
- Last Updated
- 6 years ago
Overview
Brief Summary
Oncologic patients experience anemia and anemia is associated with poor prognosis. Transfusion is associated with adverse events, and equipoise remains on the optimal transfusion strategy in oncologic patients in surgical setting. The primary objective of this study is to determine the impact of anemia and red blood cells (RBC) transfusion on post-operative complications and mortality.
Detailed Description
Between 36 and 75% of oncologic patients experience anemia and anemia is associated with poor prognosis. Up to 40% of surgical oncologic patients receive red blood cells (RBC). However, transfusion is associated with adverse events, and equipoise remains on the optimal transfusion strategy in oncologic patients in surgical setting. The primary objective of this study is to determine the impact of anemia and red blood cells (RBC) transfusion on post-operative complications and mortality. This is a retrospective, single center study. All adults admitted to the intensive care unit (ICU) after oncologic surgery within the study period are eligible.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Surgery for cancer
- •Admission to intensive care
Exclusion Criteria
- •no consent
Outcomes
Primary Outcomes
Number of mortality or any respiratory, cardiac, renal, thromboembolic, infectious and/or hemorrhagic post operative complications
Time Frame: 30 DAYS (hospital discharge)
mortality or any respiratory, cardiac, renal, thromboembolic, infectious and/or hemorrhagic post operative complications