Comparative evaluation of low-power laser and co2 laser in treatment of patients with oral lichen planus presenting to the oral Medicine Department at the Dentistry faculty in Tehran University of Medical Sciences in 1388-1389.

Research center of dental Science of Tehran University of medical sciences0 个研究点目标入组 60 人开始时间: 待定最近更新: 2018年2月22日

适应症

试验速览

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•clinical and histopathologic diagnosis of lichen planus with clinical criteria, consisting of the presence of symmetric reticular or papular lesions with or without erosive-atrophic components. Histopathologic features of oral lichen planus are: 1) Areas of hyperparakeratosis or hyperorthokeratosis, often with a thickening of the granular cell layer and a saw-toothed appearance to the retepages. 2) Liquefaction degeneration or necrosis of the basal layer. 3) A dense subepithelial band, shaped by infiltration of lymphocytes T and macrophages. 4) Absence of dysplastic changes.
•Exclusion criteria: Using drugs (including for the treatment of lichen planus at the first session) and exposure to amalgam fillings.

发起方

Research center of dental Science of Tehran University of medical sciences