The Mechanism of MicroRNAs Network in Alzheimer's Disease

Completed

• Conditions: Alzheimer Disease

• Registration Number: NCT05055310
• Lead Sponsor: Shanghai Mental Health Center

Brief Summary

MicroRNAs network, such as MicRNA107 et al, regulate the pathology of Alzheimer's disease and the clinical validation in diagnosis AD.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-10
• Primary Completion: 2019-12-31
• Study Completion: 2019-12-31
• Study First Submitted: 2020-01-08
• Status Verified: 2021-01
• Study First Submitted QC: 2021-09-21
• Last Update Submitted: 2021-09-21
• Study First Posted: 2021-09-24
• Last Update Posted: 2021-09-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 1000

Inclusion Criteria

• NIA-AA MCI due to AD clinical criteria for MCI due to AD
• NIA-AA AD clinical criteria for AD

Exclusion Criteria

• Other type of dementia

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
MicRNAs diagnosis validation for aMCI	5 years	MicRNAs concentration in plasma among three groups

Trial Locations

Locations (1)

Department of Psychogeriatrics，Shanghai Mental Health Center; 🇨🇳 Shanghai, Shanghai, China